Endocrine Abstracts

The aim of the present study was to determine the change of fasting serum leptin and insulin levels and insulin resistance in patients with risk factors of diabetes mellitus of type 2 (DM 2) including impaired glucose tolerance/impaired fasting glucose (IGT/IFG).Material and methods: The study included 100 patients (32 men, 68 female) 25–65 years old at risk factors of DM 2. All patients received recommendations on a balanced diet and physical activ...

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1.Material and methods: 191 males with DM 1 type in the age of 18–55 years. The control group included 25 almost healthy males in the age 21–41 years. The compensation of DM was estimated by the level of glycosylated hemoglobin. Also, the indicators of lipid profile, glomerular filtration rate...

The aim of the present study was to determine the change of fasting serum leptin and insulin levels and insulin resistance in patients with risk factors of diabetes mellitus of type 2 (DM 2) including impaired glucose tolerance/impaired fasting glucose (IGT/IFG), obese and first-degree relatives of patients with diabetes after lifestyle modification.Material and methods: The study included 100 patients (32 men, 68 female) 25–65 years old at risk fac...

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1.One hundred and sixty three males with DM 1 type in the age of 18–55 years (39.75±9.69) with the duration of disease more than 1 year were examined. The control group included 25 almost healthy males in the age 21–41 years (34.60±7.80). The compensation of DM was estimated by the l...

Aims: The aim of our study is to assess the efficacy of lifestyle modification in preventing diabetes mellitus type 2 (DM 2)Materials and methods: The study included 100 patients (69 m 258 f) 25–65 years with impaired glucose tolerance/impaired fasting glucose (IGT/IFG) and newly diagnosed DM 2. Patients were divided into two groups matched by sex, age, weight, BMI, waist-to-hip ratio (WHR). Research group included 54 patients who received and carri...

Aim: The aim of our study is to assess the efficacy of a lifestyle modification including altered diet composition and physical activity in preventing diabetes mellitus type 2 (DM2) in individuals with impaired glucose tolerance and impaired fasting glucose (IGT/IFG) and influence it on changes serum leptin levels.Materials and methods: The study included 327 patients with IGT/IFG (68 m, 258 f) 25-65 years. Patients were divided into two groups matched b...

Study objective: To determine risk factors of hypoglycemic episodes among patients with type 1 diabetes mellitus (T1D) using the continuous glucose monitoring system (CGMS).Materials and methods: Total 120 female patients with T1D were examined. The 1st group was with concealed hypoglycemic episodes (n=79) that has made 66% and the 2nd group was with frank hypoglycemic episodes (n=41) that has made 31% of the total number of the examined. T...

Aim: To evaluate the base-line serum sICAM-1 levels among patients with GO and levels sICAM-1 at the end of 6 month follow up after different schemes of GO treatment.Material and methods: 72 patients with GO have been surveyed. Patients have been put into 4 groups depending on spent treatment: 1st group – 26 patients received methylprednisolone per os 1 mg/kg in a combination with plasmapheresis; 2nd group – 14 patients received p...

Objective: To estimate the frequency of night time hypoglycemic reaction cases in daily monitoring of the glucose in interstitial fluid under the conditions of DM 1.Materials and methods: The study of daily glucose dynamics was conducted with the use of the continuous glucose monitoring system made by the company Medtronik Minimed, USA. The study included 113 patients with DM 1. Patients ware divided into 2 groups: group 1 with hypoglycemic reaction case...

The aim of the work was to assess the dynamics of rates of carbohydrate metabolism in DM1 in young persons.Materials and methods: The study of daily dynamics of glucose was conducted by Continuous Glucose Monitoring System. For the analysis of continuous glycaemic curve there was conducted the computation of risk index (RI) of hypoglycemia and hyperglycemia during the study period.There were examined 162 patients with DM1. First gr...